ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typebl2a_iii
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancepenicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusBacillus
COGCOG2367
Description: Beta-lactamase class A
Function: Defense mechanisms;

NCBI CDD141062
Reference1) Sloma A, et al. (1983) Molecular cloning and nucleotide sequence of the type I beta-lactamase gene from Bacillus cereus.. Nucleic Acids Res 11(14):4997-5004 PubMed: 6308567