ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typebl2a_exo
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancepenicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusStreptomyces
NCBI CDD141062
Reference1) Dehottay P, et al. (1987) Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor.. Eur J Biochem 166(2):345-50 PubMed: 3038538