ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl2_len
DescriptionClass A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancepenicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusKlebsiella
Staphylococcus
NCBI CDD141062
Reference1) Arakawa Y, et al. (1986) Close evolutionary relationship between the chromosomally encoded beta-lactamase gene of Klebsiella pneumoniae and the TEM beta-lactamase gene mediated by R plasmids.. FEBS Lett 207(1):69-74 PubMed: 3533626