ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl1_sm
DescriptionClass C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusSerratia
COGCOG1680
Description: Beta-lactamase class C and other penicillin binding proteins
Function: Defense mechanisms;

NCBI CDD141062
Reference1) Nomura K, et al. (1990) Nucleotide sequence of the Serratia marcescens SR50 chromosomal ampC beta-lactamase gene.. FEMS Microbiol Lett 58(3):295-9 PubMed: 2227364