ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl1_och
DescriptionClass C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusOchrobactrum
COGCOG1680
Description: Beta-lactamase class C and other penicillin binding proteins
Function: Defense mechanisms;

NCBI CDD31866: AmpC
141062
Reference1) Nadjar D, et al. (2001) Molecular characterization of chromosomal class C beta-lactamase and its regulatory gene in Ochrobactrum anthropi.. Antimicrob Agents Chemother 45(8):2324-30 PubMed: 11451692