ARDB-Antibiotic Resistance Genes Database

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Resistance Typebl1_acc
DescriptionClass C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Antibiotic Resistancecephalosporin
e_penicillin
Gene Ontology (GO)Molecular Function
beta-lactamase activity [GO:0008800]


Biological Process
beta lactam resistance [AR:0000048]
drug enzymatic destruction [AR:0001004]
Found in GenusEscherichia
Hafnia
Klebsiella
Salmonella
COGCOG1680
Description: Beta-lactamase class C and other penicillin binding proteins
Function: Defense mechanisms;

NCBI CDD31866: AmpC
141062
Reference1) Bauernfeind A, et al. (1999) A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia.. Antimicrob Agents Chemother 43(8):1924-31 PubMed: 10428914