ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaph33ib
DescriptionAminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
Antibiotic Resistancestreptomycin
Gene Ontology (GO)Molecular Function
aminoglycoside phosphotransferase activity [GO:0034071]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Actinobacillus
Aeromonas
Alcaligenes
Avibacterium
Bibersteinia
Bordetella
Corynebacterium
Erwinia
Escherichia
Haemophilus
Klebsiella
Listeria
Mannheimia
Pasteurella
Pseudomonas
Pseudomonas syringae group
Psychrobacter
Salmonella
Shigella
Vibrio
Xanthomonas
Yersinia
NCBI CDD110623
88613: APH
Reference PubMed: 11083623
2) Oka A, et al. (1981) Nucleotide sequence of the kanamycin resistance transposon Tn903.. J Mol Biol 147(2):217-26 PubMed: 6270337
 PubMed: 8385262