ARDB-Antibiotic Resistance Genes Database

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Resistance Typeant3ia
DescriptionAminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
Antibiotic Resistancespectinomycin
streptomycin
Gene Ontology (GO)Molecular Function
aminoglycoside nucleotidyltransferase activity [GO:0034068]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Acidovorax
Acinetobacter
Aerococcus
Aeromonas
Bacillus
Burkholderia
Chryseobacterium
Citrobacter
Corynebacterium
Elizabethkingia
Enterobacter
Enterococcus
Escherichia
Klebsiella
Kluyvera
Morganella
other sequences
Pannonibacter
Pantoea
Pasteurella
Proteus
Pseudomonas
Raoultella
Riemerella
Salmonella
Serratia
Shigella
Vibrio
Yersinia
NCBI CDD140897
Reference PubMed: 11083623
2) Hollingshead S, et al. (1985) Nucleotide sequence analysis of a gene encoding a streptomycin/spectinomycin adenylyltransferase.. Plasmid 13(1):17-30 PubMed: 2986186
 PubMed: 8385262