ARDB-Antibiotic Resistance Genes Database

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Resistance Typeamra
Resistance Requirementamrb    opra    
DescriptionResistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Antibiotic Resistanceacriflavine
aminoglycoside
macrolide
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]


Biological Process
acriflavin resistance [AR:0000045]
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
aminoglycoside resistance [AR:0000016]
macrolide resistance [AR:0000033]


Cellular Component
membrane part [GO:0044425]
Found in GenusBurkholderia
COGCOG845
Description: Membrane-fusion protein
Function: Cell wall/membrane/envelope biogenesis;

NCBI CDD137397
Reference1) Moore RA, et al. (1999) Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.. Antimicrob Agents Chemother 43(3):465-70 PubMed: 10049252