ARDB-Antibiotic Resistance Genes Database

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Resistance Typeadeb
Resistance Requirementadec    adea    
DescriptionResistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Antibiotic Resistanceaminoglycoside
chloramphenicol
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]
ABC-type efflux porter activity [GO:0015427]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
aminoglycoside resistance [AR:0000016]


Cellular Component
membrane part [GO:0044425]
Found in GenusAcinetobacter
COGCOG841
Description: Cation/multidrug efflux pump
Function: Defense mechanisms;

NCBI CDD129993
142644
Reference1) Magnet S, et al. (2001) Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454.. Antimicrob Agents Chemother 45(12):3375-80 PubMed: 11709311