ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaac6iia
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistancedibekacin
gentamicin
netilmicin
sisomicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Acinetobacter
Aeromonas
Chryseobacterium
Elizabethkingia
Klebsiella
Pseudomonas
Riemerella
Salmonella
NCBI CDD119390
118852
Reference PubMed: 11083623
2) Shaw KJ, et al. (1989) Isolation, characterization, and DNA sequence analysis of an AAC(6')-II gene from Pseudomonas aeruginosa.. Antimicrob Agents Chemother 33(12):2052-62 PubMed: 2515793
 PubMed: 8385262