ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaac6ic
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistanceamikacin
dibekacin
isepamicin
netilmicin
sisomicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusSerratia
NCBI CDD119390
Reference1) Shaw KJ, et al. (1992) Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens.. Antimicrob Agents Chemother 36(7):1447-55 PubMed: 1354954
 PubMed: 11083623
 PubMed: 8385262