ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaac6ib
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistanceamikacin
dibekacin
isepamicin
netilmicin
sisomicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAchromobacter
Acinetobacter
Aeromonas
Agrobacterium
Burkholderia
Campylobacter
Citrobacter
Enterobacter
Escherichia
Klebsiella
Kluyvera
Morganella
Proteus
Providencia
Pseudomonas
Psychrobacter
Salmonella
Serratia
Shigella
Staphylococcus
Stenotrophomonas
Vibrio
Yersinia
NCBI CDD119390
140897
Reference PubMed: 11083623
2) Tran van Nhieu G, et al. (1987) Primary structure of an aminoglycoside 6'-N-acetyltransferase AAC(6')-4, fused in vivo with the signal peptide of the Tn3-encoded beta-lactamase.. J Bacteriol 169(12):5708-14 PubMed: 2824444
 PubMed: 8385262