ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaac6i
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistanceamikacin
dibekacin
isepamicin
netilmicin
sisomicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
COGCOG456
Description: Acetyltransferases
Function: General function prediction only;

NCBI CDD119390
30804: RimI
Reference1) Lambert T, et al. (1994) Characterization of the chromosomal aac(6')-Ij gene of Acinetobacter sp. 13 and the aac(6')-Ih plasmid gene of Acinetobacter baumannii.. Antimicrob Agents Chemother 38(9):1883-9 PubMed: 7810994
 PubMed: 11083623
 PubMed: 8385262