ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typeaac3iv
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistanceapramycin
dibekacin
gentamicin
netilmicin
sisomicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusCampylobacter
Escherichia
Pseudomonas
Salmonella
NCBI CDD120344
Reference1) Bräu B, et al. (1984) Genes for gentamicin-(3)-N-acetyltransferases III and IV: I. Nucleotide sequence of the AAC(3)-IV gene and possible involvement of an IS140 element in its expression.. Mol Gen Genet 193(1):179-87 PubMed: 6318050
 PubMed: 11083623
 PubMed: 8385262