ARDB-Antibiotic Resistance Genes Database

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Resistance Typeaac3ia
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistanceastromicin
gentamicin
sisomicin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusAcinetobacter
Burkholderia
Escherichia
Klebsiella
Proteus
Pseudomonas
Salmonella
Serratia
Streptomyces
NCBI CDD119390
Reference PubMed: 11083623
2) Cameron FH, et al. (1986) Nucleotide sequence of the AAD(2'') aminoglycoside adenylyltransferase determinant aadB. Evolutionary relationship of this region with those surrounding aadA in R538-1 and dhfrII in R388.. Nucleic Acids Res 14(21):8625-35 PubMed: 3024112
 PubMed: 8385262