ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance Typeaac2ic
DescriptionAminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
Antibiotic Resistance6_n_netilmicin
dibekacin
gentamicin
netilmicin
tobramycin
Gene Ontology (GO)Molecular Function
aminoglycoside N-acetyltransferase activity [GO:0034069]


Biological Process
aminoglycoside resistance [AR:0000016]
drug enzymatic destruction [AR:0001004]
Found in GenusMycobacterium
COGCOG456
Description: Acetyltransferases
Function: General function prediction only;

NCBI CDD119390
Reference PubMed: 11083623
2) Aínsa JA, et al. (1997) Aminoglycoside 2'-N-acetyltransferase genes are universally present in mycobacteria: characterization of the aac(2')-Ic gene from Mycobacterium tuberculosis and the aac(2')-Id gene from Mycobacterium smegmatis.. Mol Microbiol 24(2):431-41 PubMed: 9159528
 PubMed: 8385262