ARDB-Antibiotic Resistance Genes Database

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Resistance TypeVgaA
DescriptionABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Antibiotic Resistancestreptogramin_a
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]
ABC-type efflux porter activity [GO:0015427]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
lincomycin resistance [AR:0000046]
macrolide resistance [AR:0000033]
streptogramin b resistance [AR:0000050]


Cellular Component
membrane part [GO:0044425]
Found in GenusStaphylococcus
NCBI CDD72980: ABCF_EF-3
109074
Reference PubMed: 10582867
2) Allignet J, et al. (1992) Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics.. Gene 117(1):45-51 PubMed: 1644314