ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance TypeErmW
DescriptionrRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
Antibiotic Resistancelincosamide
macrolide
streptogramin_b
Gene Ontology (GO)Molecular Function
rRNA (adenine-N6-)-methyltransferase activity [GO:0008988]


Biological Process
roxithromycin resistance [AR:0000027]
glycylcycline resistance [AR:0000042]
erythromycin resistance [AR:0000006]
drug target modification [AR:0001001]
Found in GenusMicromonospora
NCBI CDD140359
100107
Reference1) Inouye M, et al. (1994) Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida.. Gene 141(1):39-46 PubMed: 8163173