ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

Resistance TypeCarA
DescriptionABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
Antibiotic Resistancelincosamide
macrolide
streptogramin_b
Gene Ontology (GO)Molecular Function
multidrug efflux pump activity [GO:0015559]
ABC-type efflux porter activity [GO:0015427]


Biological Process
resistance-nodulation-cell division (RND) drug efflux [AR:0010004]
lincomycin resistance [AR:0000046]
macrolide resistance [AR:0000033]
streptogramin b resistance [AR:0000050]


Cellular Component
membrane part [GO:0044425]
Found in GenusStreptomyces
COGCOG488
Description: ATPase components of ABC transporters with duplicated ATPase domains
Function: General function prediction only;

NCBI CDD72980: ABCF_EF-3
30834: Uup
Reference PubMed: 10582867
2) Schoner B, et al. (1992) Sequence similarity between macrolide-resistance determinants and ATP-binding transport proteins.. Gene 115(1-2):93-6 PubMed: 1612454