ARDB-Antibiotic Resistance Genes Database

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OrganismStaphylococcus aureus subsp. aureus USA300_TCH1516
Database LinkNCBI Taxon ID: 451516
NCBI Genome Project ID: 19489

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid pUSA300HOUMRNC_010063CP00073127041
chromosomeNC_010079CP0007302872915


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001569062plasmid pUSA300HOUMRCAL69040100.00%aph3iiia%amikacin butirosin gentamincin_b isepamicin kanamycin lividomycin neomycin paromomycin ribostamycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_001569069plasmid pUSA300HOUMRYP_254221100.00%mphc%macrolide Macrolide phosphotransferase
YP_001573956chromosomeBAC57479100.00%mecr1%methicillin Methicillin-resistance regulatory protein for mecA
YP_001574264chromosomeBAF66599100.00%mepa%tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_001573955chromosomeABQ9663998.45%meca%beta_lactam Penicillin binding protein, which has a low affinity for beta-lactams and catalyze a penicillin-insensitive transpeptidation.
YP_001569056plasmid pUSA300HOUMRYP_00131232091.46%bl2a_pc%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001569068plasmid pUSA300HOUMRYP_25422089.75%msra%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001576184chromosomeABS7348061.31%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
YP_001569066plasmid pUSA300HOUMRABB8012859.80%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_001574690chromosomeYP_00103809448.08%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001574606chromosomeYP_00117817045.74%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001573943chromosomeCAB6122944.83%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001575566chromosomeCAL9094342.24%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001574618chromosomeBAA1260141.02%bmr%chloramphenicol fluoroquinolone Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001576487chromosomeQ83LR740.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001576262chromosomeYP_00117612840.36%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_001574065chromosomeABD2113677.56%tet3880%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.