ARDB-Antibiotic Resistance Genes Database

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OrganismActinobacillus pleuropneumoniae serovar 3 str. JL03
Database LinkNCBI Taxon ID: 434271
NCBI Genome Project ID: 19135

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_010278CP0006872242062


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001651453chromosomeYP_00143934466.67%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001651920chromosomeYP_00103809452.94%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001652843chromosomeQ83LR744.89%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001651422chromosomeQ8D9N843.74%norm%ciprofloxacin kanamycin norfloxacin streptomycin tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_001651635chromosomeYP_00143854143.10%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001651897chromosomeCAL4845743.03%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_001653077chromosomeYP_00157104142.27%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001652636chromosomeAAN8081141.67%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_001651103chromosomeCAA3747740.82%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_001652372chromosomeYP_00117612840.81%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001651594chromosomeYP_60682340.78%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Below Similarity Cutoff Genes
YP_001651244chromosomeEDK1039062.26%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001651306chromosomeYP_00144437661.59%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_001652628chromosomeYP_00145266248.84%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001652853chromosomeP5729642.78%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)