ARDB-Antibiotic Resistance Genes Database

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OrganismActinobacillus pleuropneumoniae L20
Database LinkNCBI Taxon ID: 416269
NCBI Genome Project ID: 18221

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_009053CP0005692274482


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001053108chromosomeYP_00146122367.65%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001053607chromosomeAAA8687149.02%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001053078chromosomeQ8D9N843.74%norm%ciprofloxacin kanamycin norfloxacin streptomycin tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_001053333chromosomeYP_00143854143.26%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001054716chromosomeYP_00157104143.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001053584chromosomeCAL4845743.03%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_001054296chromosomeAAN8081141.67%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_001054043chromosomeYP_00157104141.03%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001053294chromosomeYP_00118670540.77%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Below Similarity Cutoff Genes
YP_001052908chromosomeEDK1039062.26%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001052968chromosomeYP_00144437661.59%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_001054288chromosomeYP_00145266248.84%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001054510chromosomeP5729642.38%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)