ARDB-Antibiotic Resistance Genes Database

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OrganismEnterobacter sp. 638
Database LinkNCBI Taxon ID: 399742
NCBI Genome Project ID: 17461

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid pENTE01NC_009425CP000654157749
chromosomeNC_009436CP0006534518712


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001175338chromosomeYP_001175338100.00%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001178170chromosomeYP_001178170100.00%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001176513chromosomeYP_00117651397.37%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001176128chromosomeYP_00117612897.06%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001178158chromosomeYP_00117815896.78%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001175677chromosomeYP_00117567796.00%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001176127chromosomeYP_00117612795.24%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001175678chromosomeYP_00117567891.18%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001176309chromosomeYP_00117630990.30%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001175078chromosomeBAA3207779.44%bl1_ampc%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001178851chromosomeYP_00145166978.26%mdtl%chloramphenicol Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001174764chromosomeYP_00117476477.41%emrd%emre Multidrug resistance efflux pump.
YP_001176804chromosomeQ32DT376.71%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001178413chromosomeYP_15144575.27%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001175692chromosomeYP_00147737772.56%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001178412chromosomeCAC3572464.58%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001175693chromosomeYP_00147737864.25%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001176263chromosomeP0764164.19%cata4%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
YP_001177680chromosomeABG7796663.96%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001175587chromosomeYP_00133473062.66%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001175130chromosomeYP_00103809458.74%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001176620chromosomeYP_28702654.58%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001176226chromosomeCAJ7784453.71%adeb%aminoglycoside chloramphenicol adea adec Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001175674chromosomeAAK8871252.46%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_001177372chromosomeNP_84816747.37%catb2%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_001177385chromosomeAAK8871245.61%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_001176619chromosomeYP_00134810545.43%mexe%chloramphenicol fluoroquinolone mexf oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001176362chromosomeYP_00145376043.38%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001177224chromosomeYP_00117612843.19%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001176798chromosomeQ8ZQE440.87%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001176066chromosomeZP_0072985040.51%%
Below Similarity Cutoff Genes
YP_001175501chromosomeYP_00144437666.67%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_001175902chromosomeAAX6582358.46%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001178515chromosomeYP_00129003352.94%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001175427chromosomeP5729652.13%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001178351chromosomeYP_00129003340.48%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001175368chromosomeAAP4660340.27%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)