ARDB-Antibiotic Resistance Genes Database

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OrganismBurkholderia multivorans ATCC 17616
Database LinkNCBI Taxon ID: 395019
NCBI Genome Project ID: 17407

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid pBMUL01NC_010070CP000871167422
chromosome 1NC_010084CP0008683448466
chromosome 2NC_010086CP0008692472928
chromosome 3NC_010087CP000870919806


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001583350chromosome 2YP_00158335092.37%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001579800chromosome 1ZP_0155925691.87%%
YP_001579799chromosome 1ZP_0098253782.24%%
YP_001583349chromosome 2ZP_0156388582.08%%
YP_001583351chromosome 2YP_00158335181.76%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001579801chromosome 1ZP_0156286671.69%%
YP_001578881chromosome 1YP_00147735863.69%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001580055chromosome 1CAL2169361.72%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001584328chromosome 2CAD1746460.79%mexc%erythromycin fluoroquinolone glycylcycline roxithromycin mexd oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001583665chromosome 2CAJ4342258.45%bl2e_y56%cephalosporin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001579596chromosome 1YP_85336156.33%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001584329chromosome 2CAJ7784455.89%adeb%aminoglycoside chloramphenicol adea adec Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001583906chromosome 2YP_28702655.61%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001578783chromosome 1ABG6809553.53%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001578880chromosome 1YP_00117567853.41%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001579858chromosome 1BAB3503749.53%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_001585958chromosome 3AAS0701749.44%bl1_sm%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001578882chromosome 1BAA2869448.25%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001583307chromosome 2AAA7339246.44%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_001584330chromosome 2ZP_0096707445.35%%
YP_001579597chromosome 1YP_00146360243.31%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001579031chromosome 1AAA5032542.86%oleb%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001584021chromosome 2ZP_0083485442.61%%
YP_001580354chromosome 1ABN7941742.54%tetw%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_001578398chromosome 1ZP_0072892142.53%%
YP_001580655chromosome 1CAD0773042.11%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001580403chromosome 1CAL4845742.07%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_001583905chromosome 2YP_00134810541.48%mexe%chloramphenicol fluoroquinolone mexf oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001579933chromosome 1CAA3747740.85%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_001584351chromosome 2YP_00147737740.60%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001578439chromosome 1AAL0982640.15%tetw%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Below Similarity Cutoff Genes
YP_001583308chromosome 2EDJ9155545.49%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001581023chromosome 1AAP4659744.38%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001584350chromosome 2AAP4662243.03%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001578482chromosome 1ZP_0015544242.39%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001579506chromosome 1ZP_0015544241.02%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)