ARDB-Antibiotic Resistance Genes Database

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OrganismPseudomonas aeruginosa PA7
Database LinkNCBI Taxon ID: 381754
NCBI Genome Project ID: 16720

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_009656CP0007446588339


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001346278chromosomeYP_001346278100.00%mexh%mexi opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001350669chromosomeABS71065100.00%aph6id%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_001350672chromosomeCAC08522100.00%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_001345921chromosomeYP_00134592198.47%mexb%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001349899chromosomeYP_00134989997.51%%
YP_001345920chromosomeYP_00134592097.51%mexa%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexb oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001346370chromosomeYP_00134637094.71%bl1_pao%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001350280chromosomeYP_00135028094.50%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001348630chromosomeYP_00134863094.16%mexy%aminoglycoside glycylcycline mexx oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001350570chromosomeYP_00135057093.47%oprj%erythromycin fluoroquinolone glycylcycline roxithromycin mexc mexd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001350571chromosomeYP_00135057193.38%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001345922chromosomeYP_00134592292.78%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001348629chromosomeYP_00134862992.61%mexx%aminoglycoside glycylcycline mexy oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001348104chromosomeYP_00134810491.53%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001346277chromosomeYP_00134627788.82%mexi%mexh opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001348105chromosomeYP_00134810586.96%mexe%chloramphenicol fluoroquinolone mexf oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001349073chromosomeAAA7339284.21%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_001348103chromosomeYP_00134810378.81%oprn%chloramphenicol fluoroquinolone mexe mexf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001346975chromosomeYP_00146360268.92%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001350143chromosomeZP_0096522768.82%%
YP_001349541chromosomeP5877756.19%cata1%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
YP_001351630chromosomeYP_00147737755.76%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001347009chromosomeYP_27448155.39%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001348631chromosomeYP_44296453.83%opra%acriflavine aminoglycoside macrolide amra amrb Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001346131chromosomeYP_00146122353.10%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001348792chromosomeAAA7339250.76%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_001348697chromosomeYP_00117817049.41%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001345838chromosomeCAL4845748.15%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_001346643chromosomeZP_0096522747.97%%
YP_001350566chromosomeYP_00157104145.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001348230chromosomeYP_00157104145.35%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001347842chromosomeYP_79231644.68%%
YP_001345664chromosomeAAS1831443.53%%
YP_001349080chromosomeABG3670043.20%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_001349376chromosomeYP_00133566242.63%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001345638chromosomeYP_00134989942.42%%
YP_001349331chromosomeEAZ6268242.40%%
YP_001350572chromosomeABR1327042.20%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001350825chromosomeABA7172741.77%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001349146chromosomeAAN8081141.25%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_001348094chromosomeYP_00134989941.03%%
YP_001351655chromosomeAAK6445440.98%bl1_sm%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001347474chromosomeYP_00134989940.44%%
YP_001347546chromosomeYP_00145376040.27%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_001351101chromosomeYP_00129003344.46%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001346492chromosomeYP_00145266241.81%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)