ARDB-Antibiotic Resistance Genes Database

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OrganismRalstonia eutropha H16
Database LinkNCBI Taxon ID: 381666
NCBI Genome Project ID: 13603

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid megaplasmid pHG1NC_005241AY305378452156
chromosome 1NC_008313AM2604794052032
chromosome 2NC_008314AM2604802912490


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_840635chromosome 2YP_28702667.95%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_726250chromosome 1YP_77658267.60%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_724595chromosome 1ZP_0083476360.11%%
YP_840634chromosome 2ZP_0156388559.94%%
YP_840821chromosome 2ABF5090957.34%bl1_och%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_841157chromosome 2YP_85336157.01%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_725928chromosome 1YP_85336157.01%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_726996chromosome 1YP_00147737756.83%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_728154chromosome 1ABG7796654.96%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_726249chromosome 1ZP_0156388552.60%%
YP_725032chromosome 1ABG6809548.71%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_841125chromosome 2Q8ZQE445.97%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_726758chromosome 1CAA3747745.77%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_727054chromosome 1CAA0558845.63%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_841651chromosome 2YP_00157104145.45%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_840636chromosome 2YP_00111603044.71%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_728155chromosome 1YP_44296444.63%opra%acriflavine aminoglycoside macrolide amra amrb Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_727151chromosome 1CAL4845744.51%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_728030chromosome 1YP_44296543.69%amrb%acriflavine aminoglycoside macrolide amra opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_728153chromosome 1ABR1327043.69%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_728944chromosome 2ZP_0096707443.61%%
YP_842074chromosome 2AAX1928242.16%vansa%teicoplanin vancomycin vana vanha vanra vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_727203chromosome 1Q83LR742.08%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_724986chromosome 1YP_00157104142.02%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_727315chromosome 1CAD0773041.96%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_726251chromosome 1YP_77658141.61%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_725326chromosome 1YP_00143854141.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_726290chromosome 1ABK8618840.61%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_841012chromosome 2Q0098340.08%bl2d_lcr1%cloxacillin penicillin Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
Below Similarity Cutoff Genes
YP_725181chromosome 1EDJ9155553.33%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_727721chromosome 1CAD7059244.55%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_727877chromosome 1YP_00129003340.87%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)