ARDB-Antibiotic Resistance Genes Database

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OrganismAeromonas hydrophila subsp. hydrophila ATCC 7966
Database LinkNCBI Taxon ID: 380703
NCBI Genome Project ID: 16697

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_008570CP0004624744448


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_855286chromosomeYP_855286100.00%bl3_cpha%carbapenem cephalosporin cephamycin penicillin Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_857635chromosomeYP_85763594.33%bl1_ceps%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_858532chromosomeCAL1370573.56%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_855536chromosomeQ32DT369.53%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_855484chromosomeCAE1290467.54%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_857414chromosomeYP_00133412567.05%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_857552chromosomeYP_00147737762.09%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_857415chromosomeCAC3572458.09%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_854581chromosomeYP_00147737857.51%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_855395chromosomeYP_00117630954.77%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_854562chromosomeNP_84816754.09%catb2%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_855861chromosomeZP_0094614353.70%mexc%erythromycin fluoroquinolone glycylcycline roxithromycin mexd oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_855860chromosomeAAL1444053.31%adeb%aminoglycoside chloramphenicol adea adec Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_857413chromosomeYP_00134592251.90%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_857494chromosomeQ5PGK951.32%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_856638chromosomeBAA3145651.13%norm%ciprofloxacin kanamycin norfloxacin streptomycin tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_857844chromosomeAAK8871251.02%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_858214chromosomeYP_00143650750.00%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_857242chromosomeCAA3903848.59%aac6if%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_855302chromosomeYP_00117612847.98%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_856475chromosomeCAA0558846.91%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_856249chromosomeYP_00157278546.12%emrd%emre Multidrug resistance efflux pump.
YP_854820chromosomeABO9358746.05%qnra%fluoroquinolone Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
YP_857464chromosomeYP_00163312745.90%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_855138chromosomeAAK8871245.45%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_856537chromosomeYP_00117612844.70%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_857493chromosomeYP_00143854244.25%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_856714chromosomeAAL2744543.90%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_858112chromosome1XAT43.69%catb4%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_855301chromosomeYP_00133457743.33%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_858675chromosomeAAO2460043.15%bl2d_oxa9%cloxacillin penicillin Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_854550chromosomeYP_00118670542.79%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_854947chromosomeAAL2744542.74%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_858265chromosomeYP_00138962142.25%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_857866chromosomeCAL4845742.07%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_857307chromosomeAAX6480340.49%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_857592chromosomeAAL2744540.35%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
Below Similarity Cutoff Genes
YP_857913chromosomeYP_00144437660.93%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_857686chromosomeZP_0015544245.19%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_857745chromosomeYP_00157008845.03%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)