ARDB-Antibiotic Resistance Genes Database

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OrganismStreptococcus pyogenes MGAS10750
Database LinkNCBI Taxon ID: 370554
NCBI Genome Project ID: 16366

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_008024CP0002621937111


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_603198chromosomeAAB60941100.00%erma%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
YP_601965chromosomeZP_0220707057.35%vanug%vancomycin vang vanrg vansg vantg vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_602229chromosomeYP_00117612853.59%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_601918chromosomeEDK7936052.02%pmra%ciprofloxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_603312chromosomeQ8XED051.83%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_602453chromosomeYP_00137362143.51%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_602611chromosomeYP_00158879341.95%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_603310chromosomeABB5334940.93%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_602838chromosomeQ83LR740.72%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_602970chromosomeAAC9545652.79%pbp2x80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)