ARDB-Antibiotic Resistance Genes Database

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OrganismWigglesworthia glossinidia endosymbiont of Glossina brevipalpis
Database LinkNCBI Taxon ID: 36870
NCBI Genome Project ID: 274

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_004344BA000021697724
plasmid pWb1NC_003425AB0635235280


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_871279chromosomeAAX6762646.72%emrd%emre Multidrug resistance efflux pump.
NP_871541chromosomeCAB6122943.93%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_871163chromosomeYP_85336143.47%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
NP_871589chromosomeCAA7654242.31%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
Below Similarity Cutoff Genes
NP_871599chromosomeP5729653.05%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NP_871175chromosomeYP_00157008851.12%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)