ARDB-Antibiotic Resistance Genes Database

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OrganismMycobacterium vanbaalenii PYR-1
Database LinkNCBI Taxon ID: 350058
NCBI Genome Project ID: 15761

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_008726CP0005116491865


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_951157chromosomeQ4915767.98%aac2ib%6_n_netilmicin dibekacin gentamicin netilmicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_952377chromosomeEBA4353667.23%mfpa%fluoroquinolone Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
YP_953172chromosomeQ5951761.32%bl2b_tle%cephalosporin penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_955361chromosomeAAB8428259.76%tetv%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
YP_951193chromosomeAAN8081147.37%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_953138chromosomeAAB5144047.06%ermv%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
YP_953036chromosomeYP_00145376046.36%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_951848chromosomeYP_00133457845.66%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_951556chromosomeP4233244.50%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_955874chromosomeABB5336843.01%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_954670chromosomeYP_00157104142.98%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_956348chromosomeQ83LR742.92%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_955685chromosomeBAC7772541.38%tetx%tetracycline NADP-requiring oxidoreductase, an enzyme that can modify tetracycline. Mechanism detail unknown.
YP_952716chromosomeAAC6167040.45%vgbb%streptogramin_b Streptogramin B Lyase, which can deactivate the target drug by hydrolysis.
YP_954451chromosomeAAD5105640.35%vanrd%teicoplanin vancomycin vand vanhd vansd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_953201chromosomeCAL4845740.24%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.