ARDB-Antibiotic Resistance Genes Database

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OrganismVibrio cholerae O395
Database LinkNCBI Taxon ID: 345073
NCBI Genome Project ID: 15667

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosome 1NC_009456CP0006261108250
chromosome 2NC_009457CP0006273024069


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001217791chromosome 2BAC5893683.12%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_001217092chromosome 2Q8D9N869.15%norm%ciprofloxacin kanamycin norfloxacin streptomycin tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_001218711chromosome 2YP_00146122366.67%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001215635chromosome 1AAA8687164.77%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001217119chromosome 2YP_00117612852.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001216399chromosome 2AAA8687147.06%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001217937chromosome 2YP_00143650746.83%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001218436chromosome 2YP_00126629046.33%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001215559chromosome 1YP_00145376043.44%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001218231chromosome 2CAA3747742.25%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_001218708chromosome 2CAL4845742.07%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_001215223chromosome 1YP_00143854142.01%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001218404chromosome 2ABG6890940.62%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001215045chromosome 1Q83LR740.49%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_001216424chromosome 2YP_00145266249.51%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001218128chromosome 2YP_00129003346.01%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001216096chromosome 2P5729642.41%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)