ARDB-Antibiotic Resistance Genes Database

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OrganismBurkholderia cenocepacia HI2424
Database LinkNCBI Taxon ID: 331272
NCBI Genome Project ID: 13918

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosome 1NC_008542CP0004583483902
chromosome 2NC_008543CP0004592998664
chromosome 3NC_008544CP0004601055417
plasmid 1NC_008545CP000461164857


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_838977chromosome 2ZP_0156388693.69%%
YP_835268chromosome 1YP_83526891.11%amrb%acriflavine aminoglycoside macrolide amra opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_835269chromosome 1ZP_0098253789.59%%
YP_835267chromosome 1ZP_0156286685.25%%
YP_838978chromosome 2ZP_0156388584.97%%
YP_838976chromosome 2ZP_0156388779.73%%
YP_836251chromosome 1YP_00147735863.59%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_837526chromosome 2CAD1746462.60%mexc%erythromycin fluoroquinolone glycylcycline roxithromycin mexd oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_835089chromosome 1CAL2169361.72%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_839830chromosome 3YP_00147735860.42%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_837525chromosome 2CAJ7784458.50%adeb%aminoglycoside chloramphenicol adea adec Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_835506chromosome 1YP_85336156.63%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_838556chromosome 2CAJ4342256.20%bl2e_y56%cephalosporin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_838372chromosome 2YP_28702655.03%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_839702chromosome 3AAS0701754.20%bl1_sm%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_836351chromosome 1ABG6809553.90%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_836252chromosome 1EAZ6096452.69%mexa%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexb oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_839589chromosome 3ABR1327052.49%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_839590chromosome 3YP_00133412551.92%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_838581chromosome 2YP_00117612850.89%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_839829chromosome 3YP_00117567850.68%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_835204chromosome 1BAB3503750.47%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_839831chromosome 3BAA2869449.89%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_835821chromosome 1YP_00143836849.09%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_836250chromosome 1BAA2869448.95%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_838580chromosome 2YP_00143854247.89%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_833817chromosome 1YP_00158335147.62%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_839697chromosome 3ZP_0156388546.94%%
YP_835351chromosome 1YP_34848846.24%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_839065chromosome 2AAA7339245.90%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_839591chromosome 3ZP_0096707445.85%%
YP_835505chromosome 1ZP_0071684945.64%%
YP_839698chromosome 3CAJ4793045.53%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_833950chromosome 1Q3Z3Q445.05%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_834728chromosome 1CAL4845743.29%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_839628chromosome 3YP_00133457843.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_839959chromosome 3YP_00145376042.79%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_837854chromosome 2YP_00147737742.67%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_838226chromosome 2ZP_0083485442.65%%
YP_838373chromosome 2ZP_0156388542.57%%
YP_834777chromosome 1ABN7941742.54%tetw%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_837524chromosome 2YP_00134592242.42%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_838058chromosome 2Q83LR741.47%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_834563chromosome 1Q57JQ441.35%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_837011chromosome 2AAO2460040.69%bl2d_oxa9%cloxacillin penicillin Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_834705chromosome 1YP_00157104140.17%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_835152chromosome 1CAA3747740.14%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Below Similarity Cutoff Genes
YP_837290chromosome 2AAL3388655.81%cml_e390%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.
YP_834408chromosome 1AAW6649748.59%tet3980%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
YP_837855chromosome 2AAP4662244.99%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_834200chromosome 1AAP4661144.40%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_839064chromosome 2EDJ9155543.20%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_834034chromosome 1ZP_0015544242.91%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_835592chromosome 1ZP_0015544241.02%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)