ARDB-Antibiotic Resistance Genes Database

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OrganismSalmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Database LinkNCBI Taxon ID: 321314
NCBI Genome Project ID: 9618

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_006905AE0172204755700
plasmid pSCV50NC_006855AY50900349558
plasmid pSC138NC_006856AY509004138742


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_209356plasmid pSC138YP_001481442100.00%ant3ia%spectinomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
YP_209358plasmid pSC138ZP_01175305100.00%%
YP_209335plasmid pSC138ABV21787100.00%dfra12%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_209339plasmid pSC138AAF61485100.00%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_209370plasmid pSC138YP_001096379100.00%aph33ib%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_215072chromosomeAAX63991100.00%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_209316plasmid pSC138BAF42023100.00%cata2%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
YP_209353plasmid pSC138AAP82508100.00%sul3%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_209331plasmid pSC138CAH64744100.00%aph3ia%gentamincin_b kanamycin lividomycin neomycin paromomycin ribostamycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_209337plasmid pSC138ZP_0117530599.62%%
YP_216904chromosomeAAX6582397.75%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_215883chromosomeAAX6480297.58%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_215504chromosomeAAX6442397.33%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_215884chromosomeAAX6480394.75%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_209323plasmid pSC138CAL2690794.30%bl2b_tem1%cephalosporin_i cephalosporin_ii penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_216431chromosomeAAX6535094.09%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_218117chromosomeAAX6703693.60%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_218139chromosomeAAX6705892.22%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_209309plasmid pSC138CAO0028590.98%teta%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
YP_209394plasmid pSC138YP_00110196290.81%bl1_cmy2%carbapenem cefoxitin ceftazidime ceftriaxone cephalosporin cephamycin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_215505chromosomeNP_45947190.03%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_216101chromosomeAAX6502089.55%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_219359chromosomeAAX6827889.10%mdtm%acriflavine chloramphenicol norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_209357plasmid pSC138ABM6422387.11%cml_e180%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.
YP_218707chromosomeAAX6762680.71%emrd%emre Multidrug resistance efflux pump.
YP_218748chromosomeYP_00145166979.95%mdtl%chloramphenicol Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_216088chromosomeAAX6500779.70%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_215521chromosomeYP_00147737776.09%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_218315chromosomeABX6846175.94%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_209360plasmid pSC138ZP_0197465369.49%ant3ia%spectinomycin streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
YP_215522chromosomeYP_00147737865.54%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_217463chromosomeNP_75251465.44%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_216602chromosomeCAA3903858.87%aac6if%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_215410chromosomeYP_00133473055.70%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_215380chromosomeBAA2869449.35%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_209355plasmid pSC138AAN8081148.18%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_209350plasmid pSC138ABO1043547.69%mefa%macrolide Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_216634chromosomeAAN8081147.17%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_209338plasmid pSC138BAE7631846.00%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_216155chromosomeYP_00157104145.66%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_217098chromosomeABF2024045.61%catb3%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_215535chromosomeYP_00145376045.27%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_216262chromosomeAAL5102144.88%aac6ib%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_215381chromosomeYP_00134810543.87%mexe%chloramphenicol fluoroquinolone mexf oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_216942chromosomeYP_00117612841.51%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_218647chromosomeP5270041.06%bl3_l%carbapenem cephalosporin cephamycin penicillin Class B beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_215586chromosomeBAE9611440.38%vansd%teicoplanin vancomycin vand vanhd vanrd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_215847chromosomeAAX6827840.10%mdtm%acriflavine chloramphenicol norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
Below Similarity Cutoff Genes
YP_215305chromosomeYP_00144437666.00%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_215657chromosomeP7487258.27%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_218412chromosomeYP_00129003353.15%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_215177chromosomeP5729652.97%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_218251chromosomeYP_00129003341.53%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)