ARDB-Antibiotic Resistance Genes Database

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OrganismBurkholderia pseudomallei 668
Database LinkNCBI Taxon ID: 320373
NCBI Genome Project ID: 13953

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosome INC_009074CP0005703912947
chromosome IINC_009075CP0005713127456


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001058925chromosome IZP_0210890394.15%amrb%acriflavine aminoglycoside macrolide amra opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001061520chromosome IIEDP8750193.59%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001058924chromosome IAAC2775382.49%amra%acriflavine aminoglycoside macrolide amrb opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001061519chromosome IIZP_0156388579.43%%
YP_001058926chromosome IYP_00105892677.13%opra%acriflavine aminoglycoside macrolide amra amrb Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001061521chromosome IIYP_00111603075.15%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001061468chromosome IIAAD0349173.33%aac6i%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_001057906chromosome IYP_00147735863.65%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001062378chromosome IIZP_0083485458.16%%
YP_001058713chromosome ICAL2169357.14%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_001057905chromosome IYP_00143887354.97%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001057747chromosome IYP_00146122353.64%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_001059275chromosome IYP_85336153.43%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001061925chromosome IIYP_00143854151.31%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001062577chromosome IIAAG0759450.88%mexi%mexh opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001062578chromosome IIYP_00134592250.33%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001057907chromosome IYP_00134592250.22%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001058851chromosome INP_78329948.72%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_001061926chromosome IIYP_00145376148.13%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001059187chromosome IAAA5032546.15%oleb%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001064249chromosome IIYP_00145376042.08%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001062080chromosome IIZP_0096707441.76%%
YP_001059097chromosome IYP_00137362141.55%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_001061469chromosome IICAA3903841.51%aac6if%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_001060069chromosome ICAD0773040.98%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001059009chromosome IYP_00157104140.85%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001062576chromosome IIAAG0759340.68%mexh%mexi opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_001057916chromosome IAAA5032540.54%oleb%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001059274chromosome IYP_00146360240.46%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_001059802chromosome IAAV8041040.30%tett%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_001058787chromosome ICAA3747740.14%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Below Similarity Cutoff Genes
YP_001062707chromosome IIAAP4660344.54%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001061438chromosome IIEDJ9155544.53%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001060541chromosome IAAP4659742.55%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001060709chromosome IZP_0015544241.22%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001059512chromosome IP0845740.98%sta80%streptothricin Streptothricin acetyltransferase (STAT).
YP_001059401chromosome IZP_0015544240.79%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)