ARDB-Antibiotic Resistance Genes Database

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OrganismBacillus weihenstephanensis KBAB4
Database LinkNCBI Taxon ID: 315730
NCBI Genome Project ID: 13623

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid pBWB401NC_010180CP000904417054
plasmid pBWB402NC_010181CP00090575107
plasmid pBWB403NC_010182CP00090664977
plasmid pBWB404NC_010183CP00090752830
chromosomeNC_010184CP0009035262775


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_001645174chromosomeZP_01187520100.00%%
YP_001645956chromosomeZP_01187672100.00%%
YP_001645652chromosomeZP_01185695100.00%%
YP_001643158chromosomeYP_00137362188.44%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_001645260chromosomeYP_08993267.97%bl2a_iii2%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001644752chromosomeABS7348066.42%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
YP_001643697chromosomeP0080866.23%bl2a_iii2%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_001643636chromosomeBAA1235565.14%blt%chloramphenicol doxorubicin fluoroquinolone puromycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001644180chromosomeCAG7648761.19%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001645344chromosomeAAC6167160.87%vatc%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001645619chromosomeAAD2121559.69%bcrc%bacitracin bcra ABC transporter system, bacitracin efflux pump.
YP_001645070chromosomeYP_00131030358.37%cata15%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
YP_001644612chromosomeAAC6167056.80%vgbb%streptogramin_b Streptogramin B Lyase, which can deactivate the target drug by hydrolysis.
YP_001647471chromosomeAAY5200755.52%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001643156chromosomeABF0515955.19%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_001647729chromosomeAAA8687155.17%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_001646858chromosomeCAA0558853.85%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_001646859chromosomeABS7365453.40%ykkd%na_antimicrobials ykkc Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_001643145chromosomeABA7172752.36%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001645157chromosomeABA7172750.21%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001647447chromosomeAAL2744550.00%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001647277chromosomeAAK8871249.02%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_001647823chromosomeYP_00117612848.87%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001643732chromosomeBAA2222848.60%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001643598chromosomeYP_00117612848.42%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001647150chromosomeYP_00137362147.83%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_001642580plasmid pBWB401YP_03979047.11%mepa%tigecycline Multi antimicrobial extrusion (MATE) efflux family protein. Multidrug resistance efflux pump.
YP_001645216chromosomeABA7172746.82%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001647473chromosomeAAZ9883546.46%vanrd%teicoplanin vancomycin vand vanhd vansd vanxd vanyd VanD type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001645931chromosomeCAB6122445.83%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001646052chromosomeNP_84816745.03%catb2%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_001643633chromosomeABS7365344.95%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_001647966chromosomeP4233244.70%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_001643160chromosomeABK8618844.69%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001643902chromosomeAAL2744543.81%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001644583chromosomeQ5PGY043.75%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_001647152chromosomeABK8618843.48%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001645263chromosomeQ4774443.14%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001645133chromosomeQ3Z3Q443.00%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001647747chromosomeAAG0898342.99%vgaa%streptogramin_a ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001645583chromosomeCAD6019642.77%aac6ie%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_001648030chromosomeAAY5200242.54%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001644090chromosomeAAL2744542.22%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001644689chromosomeABP5733041.67%ant6ia%streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
YP_001645364chromosomeYP_00145376041.55%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001642502plasmid pBWB401YP_00157104141.28%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001647829chromosomeAAL2744541.23%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_001645751chromosomeABS7269741.15%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_001645421chromosomeQ83LR740.83%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001642436plasmid pBWB401Q4774440.70%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001642537plasmid pBWB401CAL9094340.44%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_001643202chromosomeNP_78329940.38%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_001647452chromosomeQ83LR740.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_001647206chromosomeABA7172740.17%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
Below Similarity Cutoff Genes
YP_001643352chromosomeEDJ9155546.99%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)