ARDB-Antibiotic Resistance Genes Database

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OrganismShigella dysenteriae Sd197
Database LinkNCBI Taxon ID: 300267
NCBI Genome Project ID: 13145

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_007606CP0000344369232
plasmid pSD1_197NC_007607CP000035182726
plasmid pSD197_spANC_009344CP0006408953


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_405005chromosomeYP_405005100.00%mdte%doxorubicin erythromycin mdtf tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_404013chromosomeQ32DT3100.00%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_401803chromosomeQ32K43100.00%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_405948chromosomeYP_40594897.80%mdtm%acriflavine chloramphenicol norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_405598chromosomeQ328Z896.93%mdtl%chloramphenicol Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_404705chromosomeYP_40470596.83%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_403948chromosomeABB6245796.56%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_405772chromosomeZP_0170155196.55%%
YP_403947chromosomeQ32DZ994.00%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_402154chromosomeYP_40215493.90%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_403489chromosomeQ32FA793.65%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_403670chromosomeQ32ES693.51%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_405004chromosomeYP_40500493.07%mdtf%doxorubicin erythromycin mdte tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_402153chromosomeYP_40215389.42%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_403865chromosomeABG6905988.24%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_405557chromosomeYP_40555775.76%emrd%emre Multidrug resistance efflux pump.
YP_404922chromosomeYP_00147735874.29%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_402139chromosomeYP_00147737772.99%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_404196chromosomeNP_75251464.00%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_403008chromosomeYP_00143887452.66%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_403010chromosomeZP_0096707449.62%%
YP_402157chromosomeAAK8871245.10%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
YP_403619chromosomeYP_00145376044.75%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_402104chromosomeYP_00145376042.47%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_402175chromosomeYP_00144437668.00%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_402251chromosomeYP_00145266259.38%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_401887chromosomeP5729653.30%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_405138chromosomeYP_00129003352.39%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_404871chromosomeYP_00129003344.35%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)