ARDB-Antibiotic Resistance Genes Database

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OrganismStreptococcus pyogenes MGAS10394
Database LinkNCBI Taxon ID: 286636
NCBI Genome Project ID: 12469

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_006086CP0000031899877


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_060484chromosomeABE0210196.79%mefa%macrolide Major facilitator superfamily transporter, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_059803chromosomeZP_0220707055.88%vanug%vancomycin vang vanrg vansg vantg vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
YP_059982chromosomeYP_00117612853.59%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_059756chromosomeEDK7936052.27%pmra%ciprofloxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_061045chromosomeQ8XED051.83%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_060274chromosomeYP_00158879341.95%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_061043chromosomeABB5334940.93%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
Below Similarity Cutoff Genes
YP_060731chromosomeAAC9545652.79%pbp2x80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)