ARDB-Antibiotic Resistance Genes Database

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OrganismHaemophilus influenzae 86-028NP
Database LinkNCBI Taxon ID: 281310
NCBI Genome Project ID: 11752

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_007146CP0000571914490


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_248152chromosomeYP_24815298.38%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_001621483chromosomeBAF6341895.10%bl2b_tem1%cephalosporin_i cephalosporin_ii penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_248258chromosomeYP_00143934468.73%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_248594chromosomeYP_35022142.44%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_248839chromosomeYP_00157104141.96%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_248598chromosomeCAL4845741.72%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_249048chromosomeYP_00117612841.55%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_248747chromosomeYP_00145376041.20%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_248365chromosomeYP_00144437658.06%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_248381chromosomeYP_00144437658.06%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_247695chromosomeYP_00145266250.50%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_249435chromosomeP5729641.72%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)