ARDB-Antibiotic Resistance Genes Database

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OrganismBurkholderia sp. 383
Database LinkNCBI Taxon ID: 269483
NCBI Genome Project ID: 10695

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosome 3NC_007509CP0001501395069
chromosome 1NC_007510CP0001513694126
chromosome 2NC_007511CP0001523587082


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_371056chromosome 2YP_37105693.71%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_369007chromosome 1YP_83526890.14%amrb%acriflavine aminoglycoside macrolide amra opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_369008chromosome 1ZP_0098253786.92%%
YP_371055chromosome 2ZP_0156388582.99%%
YP_371057chromosome 2YP_37105782.97%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_369006chromosome 1ZP_0156286682.32%%
YP_371952chromosome 2YP_58606169.06%mexb%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_370177chromosome 1YP_00147735865.68%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_366515chromosome 3CAD1746464.64%mexc%erythromycin fluoroquinolone glycylcycline roxithromycin mexd oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_366249chromosome 3ABF0611563.87%mdtn%acriflavine puromycin t_chloride mdto mdtp Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_366302chromosome 3YP_00147735861.10%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_368828chromosome 1CAL2169360.35%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_366514chromosome 3CAJ7784456.13%adeb%aminoglycoside chloramphenicol adea adec Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_369401chromosome 1YP_85336156.02%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_372860chromosome 2AAL5102155.17%aac6ib%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_371763chromosome 2ABE5006054.55%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_370273chromosome 1ABG6809554.28%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_371951chromosome 2EAZ6096454.19%mexa%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexb oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_367220chromosome 3AAS0701754.02%bl1_sm%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_366251chromosome 3BAE7808253.75%mdtp%acriflavine puromycin t_chloride mdtn mdto Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_371520chromosome 2AAX5564352.94%bl2e_y56%cephalosporin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_368110chromosome 1P2525652.46%tlrc%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_370178chromosome 1YP_00143887352.04%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_366301chromosome 3YP_00143887351.58%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_366303chromosome 3BAA2869450.87%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_371953chromosome 2ZP_0096707450.32%%
YP_370176chromosome 1BAA2869449.69%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_371482chromosome 2YP_00145376049.49%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_366513chromosome 3ZP_0096707447.48%%
YP_369725chromosome 1YP_00143836847.27%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_369400chromosome 1YP_00146360246.89%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_370973chromosome 2AAA7339246.69%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_369233chromosome 1YP_34848846.35%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_371483chromosome 2YP_00117612746.00%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_372003chromosome 2AAB1968445.96%bl2be_oxy1%monobactam penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_368940chromosome 1NP_78329945.12%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_367100chromosome 3YP_00143854144.14%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_367648chromosome 1Q3Z3Q443.89%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_368437chromosome 1CAL4845743.29%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_372549chromosome 2YP_00147737743.10%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_368485chromosome 1ABN7941742.54%tetw%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_370023chromosome 1P2525642.17%tlrc%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_371762chromosome 2ZP_0156388541.95%%
YP_368413chromosome 1YP_00157104141.05%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_368262chromosome 1CAD0773040.23%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_373604chromosome 2AAO2460040.17%bl2d_oxa9%cloxacillin penicillin Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_368887chromosome 1CAA3747740.14%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
Below Similarity Cutoff Genes
YP_373204chromosome 2CAJ7703248.74%cml_e390%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.
YP_368093chromosome 1AAW6649745.48%tet3980%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
YP_372546chromosome 2AAP4662243.88%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_367884chromosome 1AAP4661143.85%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_367732chromosome 1ZP_0015544242.88%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_369497chromosome 1ZP_0015544241.64%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_370974chromosome 2EDJ9155541.50%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_373285chromosome 2AAB3656840.81%cml_e695%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.