ARDB-Antibiotic Resistance Genes Database

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OrganismMesorhizobium loti MAFF303099
Database LinkNCBI Taxon ID: 266835
NCBI Genome Project ID: 18

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_002678BA0000127036071
plasmid pMLaNC_002679BA000013351911
plasmid pMLbNC_002682AP003017208315


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_104469chromosomeQ92AV857.14%fosx%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_108546chromosomeCAJ7702656.41%aph6id%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_105599chromosomeYP_00103809453.14%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_102617chromosomeAAO2460049.17%bl2d_oxa9%cloxacillin penicillin Class D beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_104386chromosomeYP_00147737748.27%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_103041chromosomeCAL4845747.88%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
NP_102994chromosomeYP_00117612847.30%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_103969chromosomeYP_00147737846.97%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_104426chromosomeAAY9251046.04%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_103684chromosomeABC6916944.22%catb3%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
NP_104715chromosomeYP_00135028044.17%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_105062chromosomeAAV8041043.75%tett%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_107696chromosomeYP_00134810443.47%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_105238chromosomeABG6890942.86%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_103472chromosomeYP_00143854142.57%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_107673chromosomeYP_00143854141.63%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_103595chromosomeAAA8687141.18%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_105510chromosomeAAK8871240.96%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
NP_107149chromosomeAAL2744540.37%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_105329chromosomeYP_00133457840.29%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_106737chromosomeAAR2161740.22%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
NP_105398chromosomeYP_00133457840.10%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_102002chromosomeBAC5893645.16%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.