ARDB-Antibiotic Resistance Genes Database

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OrganismSinorhizobium meliloti 1021
Database LinkNCBI Taxon ID: 266834
NCBI Genome Project ID: 19

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid pSymANC_003037AE0064691354226
plasmid pSymBNC_003078AL5919851683333
chromosomeNC_003047AL5916883654135


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_386394chromosomeABB4302966.15%aac3iv%apramycin dibekacin gentamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
NP_437580plasmid pSymBCAC1714963.43%bl1_och%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_384532chromosomeYP_93407362.30%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_384967chromosomeZP_0082595753.99%%
NP_384298chromosomeYP_34848853.50%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_436314plasmid pSymAP3089752.61%bl2c_bro%carbenicillin penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_436118plasmid pSymAYP_00147737751.31%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_386521chromosomeAAN8081150.59%emre%aminoglycoside emrd Multidrug resistance efflux pump.
NP_435661plasmid pSymAAAK8871250.00%catb1%chloramphenicol Group B chloramphenicol acetyltransferase, which can inactivate chloramphenicol. Also referred to as xenobiotic acetyltransferase.
NP_386490chromosomeYP_00109637949.75%aph33ib%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_385669chromosomeAAA7339247.53%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_385086chromosomeP3089747.51%bl2c_bro%carbenicillin penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_385342chromosomeAAA8687146.89%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_386861chromosomeNP_79289246.74%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_386231chromosomeCAL4845746.06%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
NP_437716plasmid pSymBCAG3426545.76%smee%fluoroquinolone smed smef Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_387196chromosomeAAV8041044.44%tett%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_386177chromosomeYP_00145376043.54%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_435852plasmid pSymAYP_00157104143.42%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_435513plasmid pSymAQ83LR742.86%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_436156plasmid pSymAAAG0588242.26%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_384299chromosomeABR1327042.21%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_386176chromosomeYP_00133457742.19%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_387105chromosomeCAF3330641.83%aph3va%neomycin paromomycin ribostamycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_437105plasmid pSymBAAK8431641.67%vatd%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_387326chromosomeYP_00145376041.63%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_385394chromosomeYP_00117612841.10%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_437868plasmid pSymBYP_93407341.09%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_385685chromosomeABS1907440.92%teta%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
NP_385400chromosomeAAK5849240.50%vanrc%vancomycin vanc vansc vant vanxyc VanC type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_384533chromosomeZP_0156388540.23%%
Below Similarity Cutoff Genes
NP_386734chromosomeAAL3388661.68%cml_e390%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.
NP_385743chromosomeBAC5893644.16%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
NP_384905chromosomeP0845741.30%sta80%streptothricin Streptothricin acetyltransferase (STAT).