ARDB-Antibiotic Resistance Genes Database

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OrganismRalstonia metallidurans CH34
Database LinkNCBI Taxon ID: 266264
NCBI Genome Project ID: 250

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
plasmid plasmid 1NC_007971CP000354233720
plasmid plasmid 2NC_007972CP000355171459
chromosome 1NC_007973CP0003523928089
chromosome 2NC_007974CP0003532580084


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_586061chromosome 2YP_58606198.09%mexb%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586060chromosome 2EAZ6096469.86%mexa%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexb oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586997chromosome 2YP_00158335068.75%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586062chromosome 2YP_00134592266.31%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_582178chromosome 1YP_00147737862.99%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_583924chromosome 1ABF5090961.86%bl1_och%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_584433chromosome 1YP_00147737761.50%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_586723chromosome 2YP_85336156.75%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_586958chromosome 2YP_85336156.23%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_585730chromosome 1ABG7796655.62%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586998chromosome 2ZP_0156388554.11%%
YP_583885chromosome 1ZP_0096707448.92%%
YP_584715chromosome 1CAL4845748.17%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_585731chromosome 1YP_44296447.70%opra%acriflavine aminoglycoside macrolide amra amrb Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586996chromosome 2ZP_0155671847.66%%
YP_582594chromosome 1ZP_0071433447.46%%
YP_585729chromosome 1YP_00117567846.02%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_583276chromosome 1YP_77341345.61%amrb%acriflavine aminoglycoside macrolide amra opra Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_584028chromosome 1YP_00145376044.85%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_584172chromosome 1CAA3747744.37%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_583940chromosome 1YP_00158879343.69%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_583196chromosome 1YP_00143854143.60%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_583836chromosome 1ZP_0096707443.17%%
YP_582548chromosome 1YP_00157104143.09%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_584847chromosome 1CAD0773043.01%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_583641chromosome 1ABG3670042.86%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_586473chromosome 2CAL9094242.42%vansa%teicoplanin vancomycin vana vanha vanra vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_582666chromosome 1YP_83897642.13%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_586722chromosome 2ZP_0071684940.93%%
YP_585160chromosome 1ABG3670040.80%sul1%sulfonamide Sulfonamide-resistant dihydropteroate synthase, which can not be inhibited by sulfonamide.
YP_587859chromosome 2YP_00158879340.30%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_582713chromosome 1EDJ9155553.33%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_585275chromosome 1CAD7059245.95%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_585415chromosome 1YP_00129003342.19%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)