ARDB-Antibiotic Resistance Genes Database

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OrganismMycobacterium smegmatis str. MC2 155
Database LinkNCBI Taxon ID: 246196
NCBI Genome Project ID: 92

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_008596CP0004806988209


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_884847chromosomeP9496891.43%aac2id%6_n_netilmicin dibekacin gentamicin netilmicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_889433chromosomeAAB8428282.82%tetv%tetracycline Major facilitator superfamily transporter, tetracycline efflux pump.
YP_886995chromosomeQ5951770.31%bl2b_tle%cephalosporin penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_886018chromosomeEBA4353666.06%mfpa%fluoroquinolone Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.
YP_886824chromosomeBAC7772557.89%tetx%tetracycline NADP-requiring oxidoreductase, an enzyme that can modify tetracycline. Mechanism detail unknown.
YP_888266chromosomeAAY9331551.60%bl1_pse%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_886024chromosomeYP_25122749.62%ermx%lincosamide macrolide streptogramin_b rRNA adenine N-6-methyltransferase, which can methylate adenine at position 2058 of 23S rRNA, conferring resistance to erythromycin.
YP_886861chromosomeYP_00145376045.45%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_885200chromosomeP4233244.98%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_890526chromosomeQ83LR743.75%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_890012chromosomeABB5336843.01%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
YP_887372chromosomeABG6890942.79%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_890933chromosomeYP_00117612841.84%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_890035chromosomeYP_00157104141.26%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_885992chromosomeYP_00157104141.01%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_887008chromosomeCAL4845740.48%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_888792chromosomeYP_00157104140.12%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
YP_890464chromosomeP3114151.80%cml_e595%chloramphenicol Major facilitator superfamily transporter, chloramphenicol efflux pump.