ARDB-Antibiotic Resistance Genes Database

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OrganismBurkholderia mallei ATCC 23344
Database LinkNCBI Taxon ID: 243160
NCBI Genome Project ID: 171

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosome 1NC_006348CP0000103510148
chromosome 2NC_006349CP0000112325379


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_106066chromosome 2EDP8750193.59%ceob%chloramphenicol ceoa opcm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_106067chromosome 2ZP_0156388579.95%%
YP_106065chromosome 2YP_00111603074.95%opcm%chloramphenicol ceoa ceob Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_102138chromosome 1YP_00147735863.55%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_105905chromosome 2ZP_0083485458.16%%
YP_102657chromosome 1CAL2169357.14%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_102137chromosome 1YP_00143887354.97%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_103049chromosome 1YP_85336153.43%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_102046chromosome 1YP_00146122353.26%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_105711chromosome 2AAG0759450.69%mexi%mexh opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_105712chromosome 2YP_00134592250.33%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_102139chromosome 1YP_00134592250.22%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_102918chromosome 1NP_78329948.72%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_102970chromosome 1AAA5032546.15%oleb%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_106003chromosome 2ZP_0096707442.73%%
YP_106593chromosome 2YP_00145376042.08%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_104978chromosome 2ZP_0098253742.04%%
YP_102709chromosome 1YP_00137362141.55%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
YP_103734chromosome 1CAD0773040.98%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_102825chromosome 1YP_00157104140.85%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_102147chromosome 1AAA5032540.54%oleb%lincosamide macrolide streptogramin_b ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
YP_106359chromosome 2CAA3903840.50%aac6if%amikacin dibekacin isepamicin netilmicin sisomicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
YP_103048chromosome 1YP_00146360240.46%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_102337chromosome 1AAV8041040.30%tett%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_105725chromosome 2YP_00147737740.26%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_102752chromosome 1CAA3747740.14%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
YP_105710chromosome 2AAG0759340.06%mexh%mexi opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Below Similarity Cutoff Genes
YP_105722chromosome 2AAP4660344.72%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_106383chromosome 2EDJ9155544.53%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_104100chromosome 1AAP4659742.55%pbp2b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_104270chromosome 1ZP_0015544241.22%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_103236chromosome 1P0845740.98%sta80%streptothricin Streptothricin acetyltransferase (STAT).
YP_103141chromosome 1ZP_0015544240.62%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)