ARDB-Antibiotic Resistance Genes Database

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OrganismStreptomyces avermitilis MA-4680
Database LinkNCBI Taxon ID: 227882
NCBI Genome Project ID: 189

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003155BA0000309025608
plasmid SAP1NC_004719AP00564594287


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_826974chromosomeBAC7350989.63%tcma%tetracenomycin_c Major facilitator superfamily transporter. Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients.
NP_825629chromosomeAAA2677558.55%bl2a_exo%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_825138chromosomeCAA0738150.50%aph6ib%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_828683chromosomeCAA3747748.45%otra%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.
NP_826607chromosomeQ83LR748.28%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_824220chromosomeAAN8081146.51%emre%aminoglycoside emrd Multidrug resistance efflux pump.
NP_826521chromosomeYP_00109629445.79%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_826565chromosomeYP_00133457845.75%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_828581chromosomeYP_00117612844.95%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_824038chromosomeP4233244.34%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_825219chromosomeABB5336844.09%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_827578chromosomeQ83LR743.11%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_828261chromosomeYP_00143854143.06%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_827171chromosomeABB5336843.04%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_823139chromosomeQ83LR742.86%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_827480chromosomeYP_00145376042.79%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_824811chromosomeYP_00158879342.66%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_822164chromosomeCAA9904942.37%aph3ic%gentamincin_b kanamycin lividomycin neomycin paromomycin ribostamycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
NP_822648chromosomeBAA0294542.02%tmrb%tunicamycin Mechanism unknown.
NP_824496chromosomeYP_00145376042.01%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_822108chromosomeYP_00137362141.74%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_828385chromosomeYP_00143854141.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_824160chromosomeYP_00117612841.13%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_827088chromosomeYP_00117612841.12%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_827958chromosomeAAQ1069741.04%qacb%qa_compound qaca Multidrug efflux pump from bacterial pathogen staphylococcus aureus. Including QacA and QacB, both of which confer resistance to various toxic organic cations but differ in that QacB mediates lower levels of resistance to divalent cations. They differed by seven nucleotide subsititutions.
NP_824703chromosomeYP_00158879340.54%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_824405chromosomeYP_00143854140.37%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_825593chromosomeAAY6797140.18%vanrc%vancomycin vanc vansc vant vanxyc VanC type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_823897chromosomeYP_93628240.11%aac2i%6_n_netilmicin dibekacin gentamicin netilmicin tobramycin Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.
NP_826940chromosomeQ83LR739.72%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_828626chromosomeCAJ8854967.90%tet80%tetracycline Ribosomal protection protein, which protects ribosome from the translation inhibition of tetracycline.