ARDB-Antibiotic Resistance Genes Database

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OrganismBacillus cereus ATCC 10987
Database LinkNCBI Taxon ID: 222523
NCBI Genome Project ID: 74

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003909AE0171945224283
plasmid pBc10987NC_005707AE017195208369


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_979752chromosomeNP_979752100.00%bl2a_1%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_979380chromosomeNP_97938098.15%%
NP_978847chromosomeP2801889.04%bl2a_iii%penicillin Class A beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
NP_977251chromosomeBAA1235565.14%blt%chloramphenicol doxorubicin fluoroquinolone puromycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_978424chromosomeABS7348064.96%fosb%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
NP_976698chromosomeABA7172663.49%vanug%vancomycin vang vanrg vansg vantg vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_977823chromosomeCAG7648762.69%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_978962chromosomeAAC6167160.29%vatc%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_979063chromosomeAAD2121559.09%bcrc%bacitracin bcra ABC transporter system, bacitracin efflux pump.
NP_978753chromosomeCAO8297458.33%cata16%chloramphenicol Group A chloramphenicol acetyltransferase, which can inactivate chloramphenicol.
NP_980581chromosomeCAA0558855.77%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_981301chromosomeAAY5200754.14%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_980582chromosomeABS7365453.85%ykkd%na_antimicrobials ykkc Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_981557chromosomeAAA8687151.72%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_976622chromosomeABA7172750.85%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_977212chromosomeYP_00117612849.77%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_979856chromosomeAAF2417149.70%vate%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
NP_981665chromosomeYP_00117612849.32%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_978872chromosomeABA7172748.94%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_978272chromosomeAAL2744548.23%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_980953chromosomeYP_00137362147.83%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_979386chromosomeYP_00133457846.40%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_981303chromosomeABA7172746.05%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_977540chromosomeCAB6122944.44%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_981821chromosomeP4233244.04%bcra%bacitracin bcrc ABC transporter system, bacitracin efflux pump.
NP_980955chromosomeABK8618843.91%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_978822chromosomeQ3Z3Q443.75%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_978259chromosomeYP_00157087143.49%mdtg%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_981576chromosomeABH1096442.86%vgaa%streptogramin_a ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_979053chromosomeQ4774442.59%vanrb%vancomycin vanb vanhb vansb vanwb vanxb vanyb VanB type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_981907chromosomeAAY5200242.54%vanra%teicoplanin vancomycin vana vanha vansa vanxa vanya VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_977734chromosomeAAL2744542.48%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_979496chromosomeBAA2222841.56%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_978361chromosomeABP5733041.30%ant6ia%streptomycin Aminoglycoside O-nucleotidylyltransferase, which modifies aminoglycosides by adenylylation.
NP_981671chromosomeAAL2744541.23%vanre%vancomycin vane vanse vante vanxye VanE type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_979521chromosomeYP_00145376041.20%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_978234chromosomeYP_00147737841.18%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_979542chromosomeABS7269741.15%lmrb%lincomycin ABC transporter system, Macrolide-Lincosamide-Streptogramin B efflux pump.
NP_977248chromosomeABS7365340.91%ykkc%na_antimicrobials ykkd Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_981013chromosomeABA7172740.59%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_977922chromosomeABA7172740.52%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
NP_978454chromosomeAAY5200740.28%vanya%teicoplanin vancomycin vana vanha vanra vansa vanxa VanA type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-lactate.
NP_981278chromosomeQ83LR740.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_978374chromosomeABA7172740.09%vanrg%vancomycin vang vansg vantg vanug vanwg vanxyg vanyg VanG type vancomycin resistance operon genes, which can synthesize peptidoglycan with modified C-terminal D-Ala-D-Ala to D-alanine--D-serine.
Below Similarity Cutoff Genes
NP_976924chromosomeEDJ9155548.09%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)