ARDB-Antibiotic Resistance Genes Database

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OrganismMannheimia succiniciproducens MBEL55E
Database LinkNCBI Taxon ID: 221988
NCBI Genome Project ID: 13068

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_006300AE0168272314078


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_087822chromosomeYP_00143934466.91%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_087609chromosomeYP_00138962152.63%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_089320chromosomeAAA8687146.15%vatb%streptogramin_a Virginiamycin A acetyltransferase, which can inactivate the target drug.
YP_087336chromosomeCAA7654246.03%qac%qa_compound Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
YP_088321chromosomeYP_00157104143.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_088506chromosomeYP_00145844743.11%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_088378chromosomeYP_00117612842.01%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_087819chromosomeABG7029241.82%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_087411chromosomeQ83LR741.23%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_087647chromosomeYP_78891240.10%mexi%mexh opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
Below Similarity Cutoff Genes
YP_089167chromosomeYP_00129239074.53%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_089309chromosomeYP_00144437663.16%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
YP_089024chromosomeYP_00157008849.92%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_088504chromosomeP5729642.94%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)