ARDB-Antibiotic Resistance Genes Database

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OrganismYersinia pestis CO92
Database LinkNCBI Taxon ID: 214092
NCBI Genome Project ID: 34

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_003143AL5908424653728
plasmid pCD1NC_003131AL11718970305
plasmid pPCP1NC_003132AL1099699612
plasmid pMT1NC_003134AL11721196210


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
NP_404135chromosomeQ66EQ899.63%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
NP_404287chromosomeCAL1932695.59%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
NP_406581chromosomeYP_00140199495.03%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_406608chromosomeCAL2172891.90%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_406580chromosomeCAL2169389.60%rosa%fosmidomycin rosb Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
NP_405953chromosomeYP_00146360271.74%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
NP_406607chromosomeYP_15144469.66%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_405928chromosomeYP_00145324769.52%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_404958chromosomeYP_00145376068.15%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_404957chromosomeYP_00157104267.40%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_404301chromosomeBAB3734667.39%tolc%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra acrb maca macb mdte mdtf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_406533chromosomeYP_00133412564.54%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_405592chromosomeYP_00143836863.82%mdth%deoxycholate fosfomycin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
NP_406941chromosomeYP_00143887455.34%acrb%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acra tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_405870chromosomeBAB3503751.82%emre%aminoglycoside emrd Multidrug resistance efflux pump.
NP_406494chromosomeYP_00145376050.07%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_406942chromosomeYP_00117567848.47%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
NP_406940chromosomeZP_0164597044.64%%
NP_405208chromosomeYP_00145376044.29%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_405083chromosomeYP_00117612843.58%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_406048chromosomeQ83LR742.47%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_404945chromosomeYP_00133457842.06%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_404003chromosomeABS7365441.25%ykkd%na_antimicrobials ykkc Small Multidrug Resistance (SMR) protein family. Multidrug resistance efflux pump, which consists of two proteins.
NP_405505chromosomeYP_00143854140.91%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_405412chromosomeYP_00143854140.76%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_406493chromosomeYP_00133457740.74%maca%macrolide macb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
NP_406569chromosomeYP_00145376040.18%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
Below Similarity Cutoff Genes
NP_406697chromosomeBAC5893663.82%tet3480%tetracycline Xanthine-guanine phosphoribosyltransferase. Mechanism detail unknown.
NP_406130chromosomeP7487257.81%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NP_406855chromosomeP5729650.93%pbp1b80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NP_403801chromosomeYP_00129003348.15%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)