ARDB-Antibiotic Resistance Genes Database

HOME DOCUMENTATION BLAST ADVANCED  SEARCH BROWSE
     Help

OrganismPseudomonas aeruginosa UCBPP-PA14
Database LinkNCBI Taxon ID: 208963
NCBI Genome Project ID: 386

Genome Information:
Replicon NameRefSeqGenBankLength(bp)
chromosomeNC_008463CP0004386537648


Resistance Genes:
GeneReplicon SourceBest HitSimilarityTypecutoffResistanceRequireDescription
Above Similarity Cutoff Genes
YP_789012chromosomeYP_789012100.00%bl1_pao%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_788600chromosomeAAG0381598.47%mexb%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_791221chromosomeYP_79122197.70%mexy%aminoglycoside glycylcycline mexx oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_792316chromosomeYP_79231697.52%%
YP_788599chromosomeEAZ6096497.13%mexa%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexb oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_788913chromosomeYP_78891396.49%mexh%mexi opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_792720chromosomeYP_79272093.22%mexw%mexv oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_788601chromosomeBAA2869492.78%oprm%aminoglycoside beta_lactam fluoroquinolone tetracycline tigecycline mexa mexb mexj mexk mexv mexw mexx mexy Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_792588chromosomeZP_0096522792.66%%
YP_793057chromosomeYP_79305792.14%mexd%erythromycin fluoroquinolone glycylcycline roxithromycin mexc oprj Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_791220chromosomeYP_79122092.08%mexx%aminoglycoside glycylcycline mexy oprm Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_790743chromosomeAAG0588291.53%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_793056chromosomeZP_0136365791.02%oprj%erythromycin fluoroquinolone glycylcycline roxithromycin mexc mexd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_788912chromosomeYP_78891288.82%mexi%mexh opmd Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_790744chromosomeAAG0588186.96%mexe%chloramphenicol fluoroquinolone mexf oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_790742chromosomeAAG0588375.21%oprn%chloramphenicol fluoroquinolone mexe mexf Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_789611chromosomeYP_00146360269.08%arna%polymyxin Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
YP_792137chromosomeQ5641556.62%fosa%fosfomycin Glutathione transferase, metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin
YP_793995chromosomeYP_00147737756.29%rosb%fosmidomycin rosa Efflux pump/potassium antiporter system. RosA: Major facilitator superfamily transporter. RosB: Potassium antiporter.
YP_791382chromosomeAAA7339254.44%aph6ic%streptomycin Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.
YP_789643chromosomeYP_27448154.39%mexf%chloramphenicol fluoroquinolone mexe oprn Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_788765chromosomeYP_00146122353.10%ksga%kasugamycin Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance.
YP_791281chromosomeCAD0773047.04%baca%bacitracin Undecaprenyl pyrophosphate phosphatase, which consists in the sequestration of Undecaprenyl pyrophosphate.
YP_788521chromosomeCAL4845746.67%dfra26%trimethoprim Group A drug-insensitive dihydrofolate reductase, which can not be inhibited by trimethoprim.
YP_793053chromosomeQ3Z3Q445.66%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_790852chromosomeYP_00157104145.55%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_790423chromosomeYP_79231644.91%%
YP_794020chromosomeAAK6445443.40%bl1_sm%cephalosporin Class C beta-lactamase. This enzyme breaks the beta-lactam antibiotic ring open and deactivates the molecule's antibacterial properites.
YP_793058chromosomeYP_85163443.32%acra%acriflavin aminoglycoside beta_lactam glycylcycline macrolide acrb tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_791713chromosomeAAN8081143.21%emre%aminoglycoside emrd Multidrug resistance efflux pump.
YP_790186chromosomeYP_00145376042.99%macb%macrolide maca tolc Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. Macrolide-specific efflux system.
YP_791884chromosomeYP_00133566242.63%mdtk%enoxacin norfloxacin Major facilitator superfamily transporter. Multidrug resistance efflux pump.
YP_788320chromosomeYP_00134989942.09%%
YP_790495chromosomeYP_00134989941.91%%
YP_790732chromosomeZP_0136433341.87%%
YP_790134chromosomeYP_00134989941.63%%
YP_790893chromosomeZP_0072892140.81%%
YP_792015chromosomeYP_41037040.35%mdtn%acriflavine puromycin t_chloride mdto mdtp Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.
YP_788345chromosomeAAS1831440.31%%
Below Similarity Cutoff Genes
YP_789116chromosomeYP_00145266241.64%pbp280%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
YP_793514chromosomeYP_00129003341.45%pbp1a80%penicillin The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)